2024 Depo shot side effects long term

May 15, 2002 · In fact, women frequently discontinue hormonal contraception because of irregular bleeding and other side effects. 1 – 3 One study 4 found that 32 percent of 1,657 women who started taking oral ... . Clara belle

Dec 1, 2009 · Olanzapine as pamoate monohydrate is a long-acting injectable or depot form of olanzapine and provides another option for maintenance treatment of schizophrenia. As with oral olanzapine, weight gain and metabolic effects (raised serum cholesterol, triglyceride and glucose levels) are common. Establish tolerability and response to oral ... puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. red skin lesions, often with a purple center. red, irritated eyes. sneezing. sore throat. sores, ulcers, or white spots in the mouth or on the lips. tightness in the chest. troubled breathing. unusual tiredness or weakness.Depo Medrol 80 MG Injection is used for treating Gout which is a type of joint inflammation. Sudden pain at night time and redness of the joints are few symptoms of Gout. Psoriasis. Depo Medrol 80 MG Injection is used to cure Psoriasis which is a type of skin disease. Itchy or sore patches and red skin are few symptoms of Psoriasis. Sep 28, 2021 · One major drawback of Depo-Provera is the continuous or irregular bleeding (spotting) that can sometimes occur during the first year. While this typically occurs during the first few months, it can persist for up to a year or longer for some people. Learn more about this side effect and what you can do if it persists. TEK IMAGE / Getty Images. some people may put on weight when they use Depo-Provera or Sayana Press contraceptive injections; you may experience side effects like headaches, acne, hair loss, decreased sex drive and mood swings; any side effects can continue for as long as the injection lasts (8 or 13 weeks) and for some time after; RisksDepo-Provera is an injection that prevents pregnancy for 3 months at a time. It contains a synthetic hormone called progestin. The birth control shot works similarly to the pill by preventing ...Aug 1, 2023 · lightening of normal skin color. pain, redness, or hard skin at the injection site. pitting or depression of the skin at the injection site. red face. reddish purple lines on the arms, face, legs, trunk, or groin. swelling of the stomach area. thinning of the scalp hair. Other side effects not listed may also occur in some patients. One major drawback of Depo-Provera is the continuous or irregular bleeding (spotting) that can sometimes occur during the first year. While this typically occurs during the first few months, it can persist for up to a year or longer for some people. Learn more about this side effect and what you can do if it persists. TEK IMAGE / Getty Images.Dec 14, 2001 · Campbell complains about serious side effects from Depo-Provera herself, so those attracted to her survey undoubtedly tend to have worries about the drug. The number one complaint was weight gain ... Mar 3, 2023 · Similar side effects of the pill vs. Depo-Provera injection. Both methods can cause tenderness or soreness in the breasts. Other side effects of oral contraceptives and the Depo-Provera shot include headaches and mood changes. Both methods can lead to a decreased interest in sex ( decreased libido) in some women. Depo-Provera Injections . Depo-Provera is a birth control injection that slowly releases progestin medroxyprogesterone acetate into your body, providing protection from pregnancy from 11 to 14 weeks. If you opt to use Depo-Provera, you will need four injections each year. The injection also comes in a generic form.Mar 3, 2023 · Similar side effects of the pill vs. Depo-Provera injection. Both methods can cause tenderness or soreness in the breasts. Other side effects of oral contraceptives and the Depo-Provera shot include headaches and mood changes. Both methods can lead to a decreased interest in sex ( decreased libido) in some women. Mar 23, 2022 · Other long-term birth control options include the: ... The Depo-Provera shot needs to be administered every three months. The birth control implant works for three years. ... Side effects usually ... Satisfaction. I'm a 40 yr. old that has been taking Depo-Provera for about 11 years. I like it all except, that I have to go to the doctor every 3 months and I do have the shakes and anxiety, heart palpitations, etc. BUT I also had anxiety before so not exactly sure if the shot is causing it. Also I do feel tired alot.Examples include birth control pills, as well as the vaginal ring (NuvaRing), skin patch (Xulane) and contraceptive injection (Depo-Provera). These are considered short-acting methods because you have to remember to use them on a daily, weekly or monthly basis. Long-acting hormonal methods.Depo Medrol 80 MG Injection is used for treating Gout which is a type of joint inflammation. Sudden pain at night time and redness of the joints are few symptoms of Gout. Psoriasis. Depo Medrol 80 MG Injection is used to cure Psoriasis which is a type of skin disease. Itchy or sore patches and red skin are few symptoms of Psoriasis.Limiting contraceptive options like DMPA may disproportionately affect adolescents and disadvantaged women. Depot medroxyprogesterone acetate inhibits the secretion of pituitary gonadotropins, resulting in anovulation and decreased production of estrogen. Decreased estrogen production is of concern because it is associated with a decrease in ...Depo-Provera is an injection that prevents pregnancy for 3 months at a time. It contains a synthetic hormone called progestin. The birth control shot works similarly to the pill by preventing ...pain, tenderness, or swelling of the foot or leg. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. severe, sudden headache. shortness of breath. slurred speech. stopping of menstrual bleeding. sudden loss of coordination. sudden, severe weakness or numbness in the arm or leg.Forty-three subjects (37% of discontinuers) restarted Depo-Provera during the study period, with a mean time to restart of 8.4 months after the last Depo-Provera injection. Side effects were the main reported reason for Depo-Provera discontinuation, primarily menstrual irregularities (26%) and weight gain (18%).LO. LousArk 25 Sep 2018. Sorry to hear it's affected you so badly. The Manufacturer acknowledges that just 1 shot can make you infertile for up to 18 months, so it's clearly still having an effect in some people for many months after stopping using it.When To See a Healthcare Provider. Signs of pregnancy after Depo-Provera ( medroxyprogesterone ) may include missed period, nausea, breast tenderness, and more. Many people are able to get pregnant around 8 to 10 months after their last Depo-Provera shot. Depo-Provera, an injectable birth control method, is more than 99% effective at preventing ...Loss of bone density, if Lupron Depot is taken long term. Convulsions (violent shaking, seizures). Problems with your heart’s electrical activity, such as long QT syndrome .The shots may be doing more harm than good. In a new study published in the journal Radiology, researchers looked at 459 patients in a US hospital who had received one to three corticosteroid ...SU. suzanne66 7 March 2010. Chemical castration (as it is referred to in males) by using Depo-provera lowers testosterone and reduces sex drive. Males can have sexual intercourse but do not want to. It also discourages sexual fantasies and eradicates sexual obsessions. Mood changes and depression are reported side-effects of depo-provera.Depo Provera (Depo medroxyprogesterone Acetate or DMPA) is a long acting progestin given by intramuscular injection every 12 weeks. It has been approved for contraception in the USA since 1992, but has been available in some countries since the 1960s. It is important to understand the benefits, risks and side effects, and to considerYou might notice: Uneven menstrual periods or no periods at all Headaches Nervousness Depression Dizziness Acne Changes in appetite Weight gain Unwanted facial and body hair Hair loss Loss of bone mineral density Belly pain Bloating Breakthrough bleeding Fatigue Less interest in sex Weakness ... Long-term case-controlled surveillance of users of Depo-Provera CI found no overall increased risk of ovarian or liver cancer. 5.4 Ectopic Pregnancy Be alert to the possibility of an ectopic pregnancy among women using Depo-Provera CI who become pregnant or complain of severe abdominal pain.Depo Provera (Depo medroxyprogesterone Acetate or DMPA) is a long acting progestin given by intramuscular injection every 12 weeks. It has been approved for contraception in the USA since 1992, but has been available in some countries since the 1960s. It is important to understand the benefits, risks and side effects, and to considerPurpose and method: Our objective is to evaluate the effects of the long-term use of depot medroxyprogesterone acetate (DMPA) as a method of contraception on bone mineral density (BMD) and bone remodeling. Forty women (21-44 years old) who used DMPA for contraception for <1, 1-2 and >5 years, in addition to 20 age-matched healthy women ...There should be confidence in that." “The long-term side effects of COVID infection are a major concern. Up to 10 percent of people who have COVID experience side effects” such as difficulty thinking, pain, tiredness, loss of taste and depression. “We don’t know why that is, how long these symptoms will last or if there are effective ...Nov 24, 2017 · LousArk 24 Nov 2017. The Manufacturer recommends that you not use Depo Provera long term (more than 2 years), unless you have no option. In that case, you need to take the recommended breaks every couple of years. They state that it can take up to 18 months from the point you miss your shot, for your fertility to return. Depo Provera (Depo medroxyprogesterone Acetate or DMPA) is a long acting progestin given by intramuscular injection every 12 weeks. It has been approved for contraception in the USA since 1992, but has been available in some countries since the 1960s. It is important to understand the benefits, risks and side effects, and to considerYou should talk to your healthcare provider about any possible side effects of Depo-Provera®. Most of these side effects are not common. Changes in your menstrual cycle is the most common side effect that women experience. You may experience irregular bleeding or spotting. After a year of use, about 50% of women will stop getting their periods.Depo-Provera Injections . Depo-Provera is a birth control injection that slowly releases progestin medroxyprogesterone acetate into your body, providing protection from pregnancy from 11 to 14 weeks. If you opt to use Depo-Provera, you will need four injections each year. The injection also comes in a generic form.Allergy shots are a form of treatment called immunotherapy. Each allergy shot contains a tiny amount of the specific substance or substances that trigger your allergic reactions. These are called allergens. Allergy shots contain just enough allergens to stimulate your immune system — but not enough to cause a full-blown allergic reaction.Depo Provera (Depo medroxyprogesterone Acetate or DMPA) is a long acting progestin given by intramuscular injection every 12 weeks. It has been approved for contraception in the USA since 1992, but has been available in some countries since the 1960s. It is important to understand the benefits, risks and side effects, and to considerHot flashes (flushing), increased sweating, night sweats, tiredness, headache, upset stomach, breast changes, acne, joint/muscle aches, trouble sleeping, reduced sexual interest, vaginal ...PIP: In Chiang Mai, Thailand, community physicians followed 2422 women who used the contraceptive injectable, Depo-Provera (DMPA), either during pregnancy and/or while breast feeding. They compared the longterm growth of the children exposed to DMPA with that of 1167 children who were not exposed to hormones during pregnancy or lactation.Summary. Commonly reported side effects of paliperidone include: akathisia, tachycardia, and drowsiness. Other side effects include: basal ganglia disease, dyskinesia, dystonia, orthostatic hypotension, postencephalitic parkinson's disease, sialorrhea, and prolonged qt interval on ecg. Continue reading for a comprehensive list of adverse effects.Depo-Provera Vial Contraceptives. - Uses, Side Effects, This medication may cause serious bone loss which may not return to normal after you stop using it. The risk of bone loss increases with ... Contraceptive implants are a long-term birth control method. They're also called long-acting reversible contraception, or LARC. A contraceptive implant is a flexible plastic rod about the size of a matchstick that is placed under the skin of the upper arm. The implant releases a low, steady dose of the hormone progestin.Feb 3, 2023 · slurred speech. stopping of menstrual bleeding. sudden loss of coordination. sudden, severe weakness or numbness in the arm or leg. sudden, unexplained shortness of breath. swelling of the fingers, hands, feet, or lower legs. troubled breathing at rest. unexpected or excess milk flow from the breasts. Jun 14, 2023 · DEPO-MEDROL is an anti-inflammatory glucocorticoid for intramuscular, intra-articular, soft tissue, or intralesional injection. It is available in three strengths: 20 mg/mL, 40 mg/mL, 80 mg/mL. Sodium Chloride was added to adjust tonicity. When necessary, pH was adjusted with sodium hydroxide and/or hydrochloric acid. Uses. Warnings: This medication may cause serious bone loss which may not return to normal after you stop using it. The risk of bone loss increases with longer use of this medication and smoking ... Contraceptive implants are a long-term birth control method. They're also called long-acting reversible contraception, or LARC. A contraceptive implant is a flexible plastic rod about the size of a matchstick that is placed under the skin of the upper arm. The implant releases a low, steady dose of the hormone progestin.Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. Eyesight changes or loss, bulging eyes, or change in how contact lenses feel. A lump in the breast, breast pain or soreness, or nipple discharge. Vaginal itching or discharge.You should talk to your healthcare provider about any possible side effects of Depo-Provera®. Most of these side effects are not common. Changes in your menstrual cycle is the most common side effect that women experience. You may experience irregular bleeding or spotting. After a year of use, about 50% of women will stop getting their periods.A further benefit of depot treatment is the achievement of stable plasma concentrations over long periods, allowing injections to be given every few weeks. However, this also represents a potential disadvantage in that there is a lack of flexibility of administration. Should adverse effects develop, the drug cannot be rapidly withdrawn.Methylprednisolone (Medrol) can cause changes in your fluids and electrolytes (e.g., sodium, potassium, and calcium). This can result in high blood pressure, swelling, and kidney problems. In addition, some studies suggest that methylprednisolone (Medrol) can damage the heart if used after a recent heart attack.You might notice: Uneven menstrual periods or no periods at all Headaches Nervousness Depression Dizziness Acne Changes in appetite Weight gain Unwanted facial and body hair Hair loss Loss of bone mineral density Belly pain Bloating Breakthrough bleeding Fatigue Less interest in sex Weakness ... Common side effects of Depo-Estradiol may include: breast pain; headache; vaginal itching or discharge, changes in your menstrual periods, breakthrough bleeding; thinning scalp hair; or. nausea, vomiting, bloating, stomach cramps. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side ...Spotting (light bleeding or brown discharge between periods) Not getting your period at all. About half of people stop getting their period while they’re on the shot (don’t worry, this is totally safe). Other possible side effects include: Nausea. Weight gain. Headaches. Sore breasts. Depression. Feb 22, 2022 · They might include: Abdominal pain Bloating Decreased interest in sex Depression Dizziness Headaches Irregular periods and breakthrough bleeding Nervousness Weakness and fatigue Weight gain Dec 15, 2010 · A prospective analysis of women using Depo-Provera found no change in sexual function after four months, and women using progestin-only pills had no difference in sexual desire compared with those ... After my very first injection 22 years ago, I have had zero periods and zero breakthrough bleeding. Zero side effects. Nothing. This has been a blessing. I had my last Depo Shot on 1/12/21. My next one is not due until 3/30/21. Today I wake up and have bleeding. Limiting contraceptive options like DMPA may disproportionately affect adolescents and disadvantaged women. Depot medroxyprogesterone acetate inhibits the secretion of pituitary gonadotropins, resulting in anovulation and decreased production of estrogen. Decreased estrogen production is of concern because it is associated with a decrease in ...PIP: In Chiang Mai, Thailand, community physicians followed 2422 women who used the contraceptive injectable, Depo-Provera (DMPA), either during pregnancy and/or while breast feeding. They compared the longterm growth of the children exposed to DMPA with that of 1167 children who were not exposed to hormones during pregnancy or lactation. Depo-Provera Vial Contraceptives. - Uses, Side Effects, This medication may cause serious bone loss which may not return to normal after you stop using it. The risk of bone loss increases with ... Mar 6, 2013 · The most common side effects associated with DMPA use are bothersome but benign and typically improve with time or upon discontinuation, including irregular bleeding, weight gain, dizziness, abdominal pain, and anxiety . Occasionally, other side effects do occur and may cause significant distress to the patient. Depo-Provera Injections . Depo-Provera is a birth control injection that slowly releases progestin medroxyprogesterone acetate into your body, providing protection from pregnancy from 11 to 14 weeks. If you opt to use Depo-Provera, you will need four injections each year. The injection also comes in a generic form.The most commonly reported side effects were hot flashes or sweats, gastrointestinal disorders, hyperhidrosis, edema, emotional lability or depression, respiratory disorder, urinary disorder, nausea or vomiting, injection site reaction, joint disorders, testicular atrophy, asthenia, flu syndrome, headache, skin reaction, fatigue, and pain.Good advice below - re: leaving your ovaries in! I had my one and only grand mal seizure on the day I got my period back - about 6 months after taking my last Depo Provera shot. I only took 2 injections of the drug but stopped it due to concerns about loss of bone density and the strange periods that I was having. Methylprednisolone (Medrol) can cause changes in your fluids and electrolytes (e.g., sodium, potassium, and calcium). This can result in high blood pressure, swelling, and kidney problems. In addition, some studies suggest that methylprednisolone (Medrol) can damage the heart if used after a recent heart attack.Methylprednisolone (Medrol) can cause changes in your fluids and electrolytes (e.g., sodium, potassium, and calcium). This can result in high blood pressure, swelling, and kidney problems. In addition, some studies suggest that methylprednisolone (Medrol) can damage the heart if used after a recent heart attack.Lupron is a drug doctors prescribe to treat prostate cancer. It works by reducing testosterone levels in the body, slowing cancer growth. Lupron is the brand name for leuprolide acetate. Lupron ...Forty-three subjects (37% of discontinuers) restarted Depo-Provera during the study period, with a mean time to restart of 8.4 months after the last Depo-Provera injection. Side effects were the main reported reason for Depo-Provera discontinuation, primarily menstrual irregularities (26%) and weight gain (18%).Long-term effects of injection Depo-Provera (depo-medroxyprogesterone acetate) on carbohydrate and lipid metabolism were studied in 157 women who were treated continuously for a mean duration of 43.3 months. The patients were matched with 162 controls for race, age, parity and height. Glucose tolerance was impaired with higher intolerance at ...Oct 1, 2022 · Lifestyle Changes. Depo-Provera ( depot medroxyprogesterone acetate , or DMPA) is an effective and relatively easy form of birth control. It does appear to cause weight gain for many women, though. Weight gain is often cited as the reason women stop using the shots. DMPA can change body composition and increase fat mass. Very common (10% or more): Increase weight (up to 37%) Common (1% to 10%): Increased appetite, decreased appetite. Uncommon (0.1% to 1%): Diabetes mellitus exacerbated, hypercalcemia, fluid retention. Frequency not reported: Elevations of serum calcium and potassium levels, exacerbation of diabetes mellitus.Depo-Provera Contraceptive Injection should not be used as a long-term birth control method (i.e., longer than 2 years) unless other birth control methods are considered inadequate. (See Warnings and Precautions (5.1)). 1 INDICATIONS AND USAGE Depo-Provera CI is indicated only for the prevention of pregnancy. The loss of bone mineral density Feb 22, 2022 · They might include: Abdominal pain Bloating Decreased interest in sex Depression Dizziness Headaches Irregular periods and breakthrough bleeding Nervousness Weakness and fatigue Weight gain A person needs a Depo-Provera shot every 3 months to ensure it remains effective in preventing pregnancy. The birth control shot, or depo shot, Depo-Provera, or DMPA, is an injection that a person ...Jan 31, 2017 · Here are a few potential side effects to be aware of if you use it. 1. You might stop having periods. The most common side effect of the shot is a change in a woman’s bleeding pattern, Jason ... Aug 7, 2023 · signs of a blood clot - sudden numbness or weakness, severe headache, chest pain, sudden cough, coughing up blood; problems with vision or speech, swelling or pain in an arm or leg. Common Depo-Provera side effects may include: changes in your menstrual periods; weakness, feeling tired; stomach pain; feeling nervous; Jan 6, 2022 · Allergy shots are a form of treatment called immunotherapy. Each allergy shot contains a tiny amount of the specific substance or substances that trigger your allergic reactions. These are called allergens. Allergy shots contain just enough allergens to stimulate your immune system — but not enough to cause a full-blown allergic reaction. Dec 15, 2010 · A prospective analysis of women using Depo-Provera found no change in sexual function after four months, and women using progestin-only pills had no difference in sexual desire compared with those ... Similar side effects of the pill vs. Depo-Provera injection. Both methods can cause tenderness or soreness in the breasts. Other side effects of oral contraceptives and the Depo-Provera shot include headaches and mood changes. Both methods can lead to a decreased interest in sex ( decreased libido) in some women.For most people, being on birth control long term is safe. Birth control can lower your risk for some cancers and raise your risk for others. It can cause blood clots, heart attacks, and strokes — but the risks are small. Being on birth control doesn’t make it harder to become pregnant once you stop it. 02:48.Olanzapine as pamoate monohydrate is a long-acting injectable or depot form of olanzapine and provides another option for maintenance treatment of schizophrenia. As with oral olanzapine, weight gain and metabolic effects (raised serum cholesterol, triglyceride and glucose levels) are common. Establish tolerability and response to oral ...Apr 25, 2023 · When To See a Healthcare Provider. Signs of pregnancy after Depo-Provera ( medroxyprogesterone ) may include missed period, nausea, breast tenderness, and more. Many people are able to get pregnant around 8 to 10 months after their last Depo-Provera shot. Depo-Provera, an injectable birth control method, is more than 99% effective at preventing ... Common side effects may include: weight gain (especially in your face or your upper back and torso); slow wound healing; muscle pain or weakness; thinning skin, increased sweating; stomach ...A further benefit of depot treatment is the achievement of stable plasma concentrations over long periods, allowing injections to be given every few weeks. However, this also represents a potential disadvantage in that there is a lack of flexibility of administration. Should adverse effects develop, the drug cannot be rapidly withdrawn.

pain, tenderness, or swelling of the foot or leg. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. severe, sudden headache. shortness of breath. slurred speech. stopping of menstrual bleeding. sudden loss of coordination. sudden, severe weakness or numbness in the arm or leg.. Resinate worcester cannabis dispensary medical and adult use photos

After my very first injection 22 years ago, I have had zero periods and zero breakthrough bleeding. Zero side effects. Nothing. This has been a blessing. I had my last Depo Shot on 1/12/21. My next one is not due until 3/30/21. Today I wake up and have bleeding.Menstrual cycle changes are the most common side effects of the Depo-Provera shot. Many individuals stop using it within the first year because of irregular spotting or bleeding. This side effect can last more than a year for some people. There is no way to predict who will experience this Depo shot side effect or how severe it may be.Long-term side effects Some diseases and medical conditions require long-term treatment with corticosteroids, at either an anti-inflammatory dose or an immunosuppressive dose. When corticosteroids will be used for more than three to four months, particularly at immunosuppressive doses, additional side effects become a concern.Depo Medrol 80 MG Injection is used for treating Gout which is a type of joint inflammation. Sudden pain at night time and redness of the joints are few symptoms of Gout. Psoriasis. Depo Medrol 80 MG Injection is used to cure Psoriasis which is a type of skin disease. Itchy or sore patches and red skin are few symptoms of Psoriasis. Warning: Blood Pressure IncreasesTestosterone undecanoate can cause blood pressure (BP) increases that can increase the risk of major adverse cardiovascular events (MACE), including non-fatal myocardial infarction, non-fatal stroke and cardiovascular death.The most commonly reported side effects were hot flashes or sweats, gastrointestinal disorders, hyperhidrosis, edema, emotional lability or depression, respiratory disorder, urinary disorder, nausea or vomiting, injection site reaction, joint disorders, testicular atrophy, asthenia, flu syndrome, headache, skin reaction, fatigue, and pain.Hot flashes (flushing), increased sweating, night sweats, tiredness, headache, upset stomach, breast changes, acne, joint/muscle aches, trouble sleeping, reduced sexual interest, vaginal ... redness of the skin. redness or swelling of the breast. sore on the skin of the breast that does not heal. swelling of the eyelids, face, fingers, lips, hands, feet, or lower legs. tightness in the chest. troubled breathing at rest. troubled breathing or swallowing. vaginal bleeding.Nov 24, 2017 · LousArk 24 Nov 2017. The Manufacturer recommends that you not use Depo Provera long term (more than 2 years), unless you have no option. In that case, you need to take the recommended breaks every couple of years. They state that it can take up to 18 months from the point you miss your shot, for your fertility to return. Apr 14, 2023 · For most people, being on birth control long term is safe. Birth control can lower your risk for some cancers and raise your risk for others. It can cause blood clots, heart attacks, and strokes — but the risks are small. Being on birth control doesn’t make it harder to become pregnant once you stop it. 02:48. There should be confidence in that." “The long-term side effects of COVID infection are a major concern. Up to 10 percent of people who have COVID experience side effects” such as difficulty thinking, pain, tiredness, loss of taste and depression. “We don’t know why that is, how long these symptoms will last or if there are effective ...Common side effects of Depo-Medrol may include: weight gain (especially in your face or your upper back and torso); slow wound healing; muscle pain or weakness; thinning skin, increased sweating; stomach discomfort, bloating; headache; or. changes in your menstrual periods. This is not a complete list of side effects and others may occur.Forty-three subjects (37% of discontinuers) restarted Depo-Provera during the study period, with a mean time to restart of 8.4 months after the last Depo-Provera injection. Side effects were the main reported reason for Depo-Provera discontinuation, primarily menstrual irregularities (26%) and weight gain (18%)..

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